4. Joe Marler (Harlequins)
A victim of the sheer amount of games since lockdown, the loosehead-prop has been battling on through an ongoing knee problem. Marler, who has openly criticised Premiership Rugby’s scheduling, hit the headlines on his last England appearance by grabbing Wales captain Alun Wyn Jones by the crotch. Bath prop Will Stuart is someone that could feature for England as a possible replacement.