In his press conference today, England head coach Eddie Jones has revealed flanker Sam Underhill got a knock in training.
Speaking ahead of their Six Nations clash with Wales at Twickenham, the Aussie revealed the injury ‘is not too serious’.
With Underhill ruled out, Mark Wilson returns at openside for the first time since the World Cup with Courtney Lawes named at blind-side flanker and Tom Curry at number 8.
Meanwhile, Jonathan Joseph misses out on the matchday squad due to selection reasons.
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England starting XV
15 Elliot Daly (Saracens, 42 caps)
14 Anthony Watson (Bath Rugby, 42 caps)
13 Manu Tuilagi (Leicester Tigers, 42 caps)
12 Owen Farrell (Saracens, 82 caps) C
11 Jonny May (Leicester Tigers, 55 caps)
10 George Ford (Leicester Tigers, 68 caps)
9 Ben Youngs (Leicester Tigers, 98 caps)
1 Joe Marler (Harlequins, 70 caps)
2 Jamie George (Saracens, 48 caps)
3 Kyle Sinckler (Harlequins, 34 caps)
4 Maro Itoje (Saracens, 37 caps)
5 George Kruis (Saracens, 44 caps)
6 Courtney Lawes (Northampton Saints, 84 caps)
7 Mark Wilson (Sale Sharks, 18 caps)
8 Tom Curry (Sale Sharks, 22 caps)
Finishers
16 Luke Cowan-Dickie (Exeter Chiefs, 23 caps)
17 Ellis Genge (Leicester Tigers, 17 caps)
18 Will Stuart (Bath Rugby, 2 caps)
19 Joe Launchbury (Wasps, 64 caps)
20 Charlie Ewels (Bath Rugby, 14 caps)
21 Ben Earl (Saracens, 2 caps)
22 Willi Heinz (Gloucester Rugby, 12 caps)
23 Henry Slade (Exeter Chiefs, 28 caps)