Eddie Jones has named his side to face Scotland in the second round of the 2020 Guinness Six Nations.
They have dropped scrum-half Ben Youngs as one of five changes made to the starting XV
Saracens pair Mako Vunipola and George Kruis have returned to the front-five, with Lewis Ludlam taking over the No 6 jersey from Courtney Lawes.
The fifth change to the line-up is injury enforced, with Jonathan Joseph replacing Manu Tuilagi in the centres.
“Preparation this week has been great. We have sought to address the issues from the France game and have had a really good and sharp preparation for Scotland,” said Jones.
“Scotland are a dangerous side. They like to play with a lot of width and with a lot of flow and tempo in their game. We want to make sure we dominate the gain line.
“Their win record against England at Murrayfield is substantially higher than their overall record against us, so we have to recognise they are a dangerous beast and we have to be at our best to beat them.”
England team to play Scotland
15 George Furbank, 14 Jonny May, 13 Jonathan Joseph, 12 Owen Farrell, 11 Elliot Daly, 10 George Ford, 9 Willi Heinz; 1 Mako Vunipola, 2 Jamie George, 3 Kyle Sinckler, 4 Maro Itoje, 5 George Kruis, 6 Lewis Ludlam, 7 Sam Underhill, 8 Tom Curry.
SUBS: 16 Tom Dunn, 17 Ellis Genge, 18 Will Stuart, 19 Joe Launchbury, 20 Courtney Lawes, 21 Ben Earl, 22 Ben Youngs, 23 Ollie Devoto