Ireland have been dealt a significant late blow ahead of Sunday’s Six Nations clash against England.
Second-row Iain Henderson has pulled out of the squad after the birth of his baby son.
Henderson’s place in the second-row will be taken by Devin Toner, who is promoted from the bench and in line to win his 70th cap.
Ultan Dillane comes into the replacements. Dillane featured for Ireland in last season’s 26-14 win against France at the Aviva Stadium.