Kieran Hardy, who has just three caps, starts in the Wales team to play England in Cardiff..
The Scarlets No 9 impressed off the bench in Wales’s round-two win over Scotland.
George North, who is returning from injury, wins his 100th Wales cap alongside Jonathan Davies at centre with the returning Davies named at 12.
Liam Williams starts at full-back with Josh Adams and Louis Rees-Zammit on the wings.
“We’ve [almost] got a full squad to choose from, which brings a headache but is also really positive,” said Wales forwards coach Jonathan Humphreys.
“Selection meetings have taken a lot longer than they did a couple of months ago.
“There are some really difficult discussions going on about combinations but that’s very positive. There’s a lot of competition for places.”
Scroll down to see the probably Wales team to play England
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Wales team to play England:
1. Wyn Jones (32 Caps)
2. Ken Owens (79 Caps)
3. Tomas Francis (54 Caps)
4. Adam Beard (23 Caps)
5. Alun Wyn Jones (CAPT) (145 Caps)
6. Josh Navidi (25 Caps)
7. Justin Tipuric (82 Caps)
8. Taulupe Faletau (83 Caps)
9. Kieran Hardy (3 Caps)
10. Dan Biggar (89 Caps)
11. Josh Adams (29 Caps)
12. Jonathan Davies (85 Caps)
13. George North (99 Caps)
14. Louis Rees-Zammit (6 Caps)
15. Liam Williams (68 Caps)
16. Elliot Dee (34 Caps)
17. Rhodri Jones (19 Caps)
18. Leon Brown (14 Caps)
19. Cory Hill (29 Caps)
20. James Botham (4 Caps)
21. Gareth Davies (59 Caps)
22. Callum Sheedy (6 Caps)
23. Uilisi Halaholo (1 Cap)
Wales v England latest odds
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When is Wales v England?
Saturday, February 27.
What time is kick-off?
The match will start at 4.45pm GMT.
What TV channel is it on – how can I watch live?
The match will be broadcast live on BBC and S4C.
LIST: Warren Gatland names the FIVE best players he’s ever coached
1. Shane Williams (Wales)
“Probably pound-for-pound, Shane Wiliams. He had some incredible brilliant attacking attributes,” Gatland said.
“But sometimes Shane could score three tries and let in two. But pound for pound he was unbelievable when he was at his best.”