England flanker Sam Underhill is the latest player to withdraw from the England squad for the Guinness Six Nations with a hip injury.
Wasps’ Jack Willis has been called up to Eddie Jones’ side for the tournament.
Yesterday, second-row Launchbury dropped out after suffering a leg injury while Marler has withdrew for personal reasons.
Head coach Eddie Jones has called up Charlie Ewels and Tom West to join the tournament squad ahead of opener against Scotland on February 6.
“Always grateful for the opportunity so not an easy decision, but want to do right by my family in these crazy times and won’t be meeting up with the squad for this tournament,” wrote Marler.
“Look forward to watching the team rip in. Go well.”
Elliot Daly (Saracens, 47 caps)
Owen Farrell (Saracens, 88 caps)
George Ford (Leicester Tigers, 72 caps)
Ollie Lawrence (Worcester Warriors, 3 caps)
Max Malins (Bristol Bears, 3 caps)
Jonny May (Gloucester Rugby, 61 caps)
Paolo Odogwu (Wasps, uncapped)
Harry Randall (Bristol Bears, uncapped)
Dan Robson (Wasps, 7 caps)
Henry Slade (Exeter Chiefs, 34 caps)
Anthony Watson (Bath Rugby, 46 caps)
Ben Youngs (Leicester Tigers, 104 caps)
Luke Cowan-Dickie (Exeter Chiefs, 26 caps)
Tom Curry (Sale Sharks, 28 caps)
Ben Earl (Bristol Bears, 8 caps)
Ellis Genge (Leicester Tigers, 23 caps)
Jamie George (Saracens, 54 caps)
Jonny Hill (Exeter Chiefs, 3 caps)
Maro Itoje (Saracens, 43 caps)
Charlie Ewels (Bath Rugby, 17 caps)
Courtney Lawes (Northampton Saints, 85 caps)
Joe Marler (Harlequins, 72 caps)
Beno Obano (Bath Rugby, uncapped)
Will Stuart (Bath Rugby, 8 caps)
Jack Willis (Wasps, 2 caps)
Billy Vunipola (Saracens, 56 caps)
Harry Williams (Exeter Chiefs, 18 caps)
Mark Wilson (Newcastle Falcons, 19 caps)
Tom West (Wasps, 0 caps)
50 players will swap countries for the 2021 Six Nations
6. England – 1 player
- Billy Vunipola (Sydney, Australia)