England head coach Eddie Jones has confirmed that Jamie George, Jack Walker and Guy Porter have been forced to withdraw from his training squad.
The Aussie has called up George McGuigan, Jack Singleton and Adam Radwan as their replacements respectively.
England will begin preparations for their four home Autumn Nations Series fixtures in November during the camp. The squad will meet in Richmond on Sunday 2 October and train at Twickenham Stadium.
First call-ups for camp include Northampton Saints’ Alex Coles and Saracens’ Hugh Tizard, both players having previously appeared for England U20s.
FORWARDS
Ollie Chessum (Leicester Tigers, 5 caps)
Alex Coles (Northampton Saints, uncapped)
Luke Cowan-Dickie (Exeter Chiefs, 37 caps)
Tom Curry (Sale Sharks, 41 caps)
Ellis Genge (Bristol Bears, 39 caps)
George McGuigan replaces Jamie George (Saracens, 69 caps)
Joe Heyes (Leicester Tigers, 5 caps)
Jonny Hill (Sale Sharks, 15 caps)
Lewis Ludlam (Northampton Saints, 14 caps)
Tom Pearson (London Irish, uncapped)
David Ribbans (Northampton Saints, uncapped)
Bevan Rodd (Sale Sharks, 2 caps)
Patrick Schickerling (Exeter Chiefs, uncapped)
Sam Simmonds (Exeter Chiefs, 14 caps)
Will Stuart (Bath Rugby, 23 caps)
Hugh Tizard (Saracens, uncapped)
Billy Vunipola (Saracens, 64 caps)
Mako Vunipola (Saracens, 70 caps)
Jack Singleton replaces Jack Walker (Harlequins, uncapped)
Jack Willis (Wasps, 4 caps)
BACKS
Henry Arundell (London Irish, 3 caps)
Joe Cokanasiga (Bath Rugby, 12 caps)
Fraser Dingwall (Northampton Saints, uncapped)
Owen Farrell (Saracens, 97 caps)
Tommy Freeman (Northampton Saints, 2 caps)
George Furbank (Northampton Saints, 6 caps)
Will Joseph (London Irish, 1 cap)
Jonny May (Gloucester Rugby, 69 caps)
Alex Mitchell (Northampton Saints, 1 cap)
Jack Nowell (Exeter Chiefs, 42 caps)
Adam Radwan replaces Guy Porter (Leicester Tigers, 2 caps)
Marcus Smith (Harlequins, 13 caps)
Freddie Steward (Leicester Tigers, 13 caps)
Manu Tuilagi (Sale Sharks, 46 caps)
Jack van Poortvliet (Leicester Tigers, 3 caps)
Ben Youngs (Leicester Tigers, 117 caps)
Also Unavailable for selection due to injury: Alfie Barbeary, Nic Dolly, Alex Dombrandt, Charlie Ewels, George Ford, Sam Jeffries, Maro Itoje, Nick Isiekwe, Courtney Lawes, Sam Underhill, Anthony Watson.
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5 stars who flopped in the Premiership this weekend
#1. Ben Youngs (Leicester Tigers)
Leicestershire Live 5/10: “He made a couple of good passes that gave two half-breaks, but a lot of passes were either above the head or slightly behind the man.”