While there are undeniably some young English players who might benefit from the huge amount of Premiership game, what about those regulars who have picked up knocks? Or struggled for game time?
Here are five England players who could miss the 2020 Autumn Nations Cup.
1. Joe Launchbury (Wasps)
The Wasps captain left the field early on his 150th appearance for the club as they breezed past Bristol Bears at the Ricoh Arena. Early signs were that it could be a pretty bad calf injury with James Gaskell replacing him. If it does prove to be serious, that would leave Jones without Launchbury and George Kruis after the Saracens star made his move to Japan.